Hi, my name is Trish , I am 167cm and weigh 130kg, I started duromine 40mg 3 days ago and so far have had no result! The only thing is I now have fluid retention, my ankles and legs are swollen, has anyone else had this happen? A lot of people seem to have results very quickly, so I am not sure if I am doing something wrong! I try to snack on protein, like a boiled egg, some fruit sometimes, and I am only having one coffee a day, but I am managing to drink 2 liters of water a day, usually with ease! Always been able to finish 1.5lt over the whole day, but since starting this I can have 2lt by lunch time!! Definatly do not feel hungry, but make myself eat something. Does anyone know if maybe celery through the day may help? I believe it is a natural diuretic? Hope someone can help me, I am desperate to get this weight off, I am not getting any younger, but at the moment I am quite healthy, no meds, or problems! Just this fluid and of course the weight!!, and I don't want to start taking fluid tabs, I think your body could become used to them.